About
What we do
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe and debilitating chronic disease. ME/CFS is common, with an estimated prevalence of over 1%, yet no cause is known and no treatments exist. Previous studies show that ME/CFS has a genetic component, and examining this provides an opportunity to elucidate phenotypic comorbidities, biologically related diseases and traits, and eventually causal biological mechanisms. The goal of this consortium is therefore to elucidate the genetic background of ME/CFS to identify novel biological disease mechanisms. We wish to collaborate with cohorts that have collected relevant genotyping data and measured clinically-defined or self-reported ME/CFS, to maximize the power of our analyses.
Featured projects
All projects →Initial DecodeME GWAS
Genome-wide association study of ME/CFS in DecodeME, with replication in UK Biobank and Lifelines.
Help us find the biology.
We are looking for members at all career stages who want to run large analyses, contribute data and write manuscripts on the genetics, omics and epidemiology of ME/CFS.
Join the consortium